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    This website is intended for healthcare professionals (HCPs) only. If you are an HCP, register free to access the full content.

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    • Vabysmo
    • About
    • nAMD
    • DME
    • RVO
    • Real-World Data
    • Mechanism of Action
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      • About
      • nAMD
      • DME
      • RVO
      • Real-World Data
      • Mechanism of Action

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    1. Ophthalmology
    2. Vabysmo
    3. About

    Faster* and greater* drying with fewer injections vs. aflibercept1-3

    Flexible dosing and extended durability1,2,4

    Powerful dual-pathway

    inhibition5-8

    *Based on post hoc, exploratory analysis with nominal P-value statistical analysis not adjusted for multiple testing (nominal P-value <0.05 vs. aflibercept 2.0 mg Q8W), no formal statistical conclusions can be drawn. Primary endpoint of Phase III studies was non-inferiority in BCVA vs. aflibercept 2.0 mg Q8W for nAMD and DME, and aflibercept 2.0 mg Q4W for RVO.

    References

    1. Khanani AM, et al. Ophthalmology. 2024;19:S0161-6420(24)00134-9.
    2. Wong TY, et al. Ophthalmology. 2024;131(6):708-723. 
    3. Chaudhary V, et al. Presented at ARVO 2023.
    4. Tadayoni R, et al. Presented at Angiogenesis 2024, presentation available at medically.roche.com.
    5. Regula JT, et al. EMBO Mol Med. 2016;8:1265–88. 
    6. Heier JS, et al. Lancet. 2022;399:729–40. 
    7. Wykoff CC, et al. Lancet. 2022;399:741–55. 
    8. VABYSMO®. SmPC https://go.roche.com/Vabysmo_SmPC Accessed May 2024.

    M-PK-00002048

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